Like Lower Mississippi River cruises, Upper Mississippi itineraries may focus on a main portion of the river, or they might add ports along other tributaries. Viking River Cruises’ eight-day New Orleans & Southern Charms cruise sails round-trip from New Orleans, visiting ports like Baton Rouge, Louisiana, and Natchez – the oldest city in Mississippi – along the way. They focus on all things Southern – from fascinating Civil War sites to thunder empire slots flavorful comfort food tours to music-themed itineraries celebrating the birthplace of the Blues. Cruises along the Lower Mississippi River typically include states like Mississippi, Louisiana and Tennessee.

Journey from St. Paul, Minnesota to New Orleans, Louisiana and explore highlights of the mighty Mississippi River. Experience curated onboard programs, live music, and the beauty of the Upper Mississippi’s diverse wildlife. Set sail for 9 days aboard American Serenade from St. Paul to St. Louis. Cruise the Columbia and Snake Rivers, visit Astoria and The Dalles, see Mount St. Helens, and explore Hells Canyon. Discover port cities such as St. Francisville, Darrow, Baton Rouge, Natchez, and Vicksburg to experience the diverse culture and rich history of the lower Mississippi region. Explore the highlights of the Mississippi River on this 8-day cruise roundtrip from New Orleans aboard Viking Mississippi.

The brand’s purpose-built Viking Mississippi translates its signature Scandinavian design and enrichment-based travel philosophy to itineraries that explore this iconic river. Finding the best river cruises in USA can feel overwhelming, with distinct regions, vessel styles, and onboard experiences to consider. Skip the endless research and information overload—our deep destination expertise helps you design a more seamless trip in a fraction of the time. The Alaska and Pacific Coast waterways, featuring glaciers, wildlife, and dramatic coastlines. Most river cruises USA has to offer range from 5 to 14 days, with the majority lasting about a week. For travelers seeking wilder frontiers, small ship US river cruises along Alaska’s coast and the Pacific Northwest offer glacier views and abundant wildlife.